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hbiostat.org
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| | Observational data from electronic health records may contain biases that large sample sizes do not overcome. Moderate confounding by indication may render an infinitely large observational study less useful than a small randomized trial for estimating relative treatment effectiveness.
| | fharrell.com
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| | Randomized clinical trials are successful because they do not mimic clinical practice. They remain highly clinically relevant despite this.
| | errorstatistics.com
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| Stephen Senn Head of Competence Center for Methodology and Statistics (CCMS) Luxembourg Institute of Health Twitter @stephensenn Being a statistician means never having to say you are certain A recent discussion of randomised controlled trials[1] by Angus Deaton and Nancy Cartwright (D&C) contains much interesting analysis but also, in my opinion, does not escape rehashing...