/explore
|
You are here 
|
hbiostat.org | ||
| | | | |
fharrell.com
|
|
| | | | | Randomized clinical trials are successful because they do not mimic clinical practice. They remain highly clinically relevant despite this. | |
| | | | |
www.fharrell.com
|
|
| | | | | Observational data from electronic health records may contain biases that large sample sizes do not overcome. Moderate confounding by indication may render an infinitely large observational study less useful than a small randomized trial for estimating relative treatment effectiveness. | |
| | | | |
www.rdatagen.net
|
|
| | | | | An investigator I frequently consult with seeks to estimate the effect of a palliative care treatment protocol for patients nearing end-stage disease, compared to a more standard, though potentially overly burdensome, therapeutic approach. Ideally, we would conduct a two-arm randomized clinical trial (RCT) to create comparable groups and obtain an unbiased estimate of the intervention effect. However, in this case, it may be considered unethical to randomize patients to a non-standard protocol. | |
| | | | |
blog.quipu-strands.com
|
|
| | | [AI summary] The text presents an extensive overview of Bayesian optimization techniques, focusing on their applications in black-box function optimization, including challenges and solutions such as computational efficiency, scalability, and integration with deep learning models. It also highlights key research contributions and references to seminal papers and authors in the field. | ||
