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hbiostat.org | ||
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www.rdatagen.net
An investigator I frequently consult with seeks to estimate the effect of a palliative care treatment protocol for patients nearing end-stage disease, compared to a more standard, though potentially overly burdensome, therapeutic approach. Ideally, we would conduct a two-arm randomized clinical trial (RCT) to create comparable groups and obtain an unbiased estimate of the intervention effect. However, in this case, it may be considered unethical to randomize patients to a non-standard protocol. |
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www.fharrell.com
Observational data from electronic health records may contain biases that large sample sizes do not overcome. Moderate confounding by indication may render an infinitely large observational study less useful than a small randomized trial for estimating relative treatment effectiveness. |
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fharrell.com
Randomized clinical trials are successful because they do not mimic clinical practice. They remain highly clinically relevant despite this. |
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www.capicua.com
Machine Learning has gained traction over the last few years, cybersecurity being one of them. Let's learn how to use it to boost your system's protection! |
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