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www.jci.org
| | insight.jci.org

[AI summary] The provided text is a list of scientific articles and research studies, primarily focused on topics related to adipose tissue, inflammation, metabolism, and fibrosis. The articles cover various aspects, including the role of matrix metalloproteinases (MMPs) in obesity, adipose tissue function, and fibrotic processes. There are also studies on peroxisome proliferator-activated receptors (PPARs), their involvement in metabolic regulation, and their anti-fibrotic effects. The text includes references to gene expression, signaling pathways, and the impact of diet and environmental factors on metabolic health.
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| | diabetesjournals.org

OBJECTIVE. Glucose-dependent insulinotropic polypeptide (GIP), unlike glucagon-like peptide (GLP)-1, lacks glucose-lowering properties in patients with type 2 d
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| | www.frontiersin.org

Iron is a critical element for living cells in terrestrial life. Although iron metabolism is strictly controlled in the body, disturbance of iron homeostasis under certain type of condition leads to innate and adaptive immune response. In innate immunity, iron regulates macrophage polarizations, neutrophils recruitment, and NK cells activity. In adaptive immunity, iron had an effect on the activation and differentiation of Th1, Th2, and Th17 and CTL, and antibody response in B cells. In this review, we focused on iron and immune regulation and listed the specific role of iron in macrophage polarization, T-cell activation, and B-cells antibody response. In addition, correlations between iron and several diseases such as cancer and aging degenerative diseases ...
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| | www.cureffi.org

20 years after the discovery of RNA interference, the first drug is approved. Great news, but our path forward for prion disease remains unchanged.
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