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JCI Insight - Fat fibrosis: friend or foe?
| | www.jci.org
JCI - Cell dysfunction during progression of metabolic syndrome to type 2 diabetes
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| | www.frontiersin.org
Frontiers | Iron Metabolism and Immune Regulation
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| | Iron is a critical element for living cells in terrestrial life. Although iron metabolism is strictly controlled in the body, disturbance of iron homeostasis under certain type of condition leads to innate and adaptive immune response. In innate immunity, iron regulates macrophage polarizations, neutrophils recruitment, and NK cells activity. In adaptive immunity, iron had an effect on the activation and differentiation of Th1, Th2, and Th17 and CTL, and antibody response in B cells. In this review, we focused on iron and immune regulation and listed the specific role of iron in macrophage polarization, T-cell activation, and B-cells antibody response. In addition, correlations between iron and several diseases such as cancer and aging degenerative diseases ...
| | www.jci.org
JCI - In_press_preview
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| | spinstrangenesscharm.wordpress.com
COVID19, April 15, 2020 update: Cytokine storm - the immune system "killing the patient in order to save him/her" | Spin, strangeness, and charm
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| The more I read about the (fairly rare) cases of younger people in generally good health dying or becoming critically ill, the more it sounded to me like "cytokine storm", a.k.a. https://en.wikipedia.org/wiki/Cytokine_release_syndrome In plain English, this is what happens when the immune system massively overreacts and does more damage to the patient than the original...