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www.wiringthebrain.com
| | milan.cvitkovic.net

Some strategic considerations for pursuing human longevity
3.6 parsecs

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| | berkeleygenomics.org

[AI summary] The provided text outlines a comprehensive roadmap for advancing human germline genomic engineering (GE) and epigenomic correction (EC). It emphasizes the need for understanding primate reproductive epigenomics to develop safe and effective methods for creating genetically modified human embryos. The process involves several key steps: (1) building an epigenomic atlas of primate and human reproduction to establish gold standards for healthy epigenomic states, (2) testing these methods in non-human primates to ensure safety and efficacy, (3) applying these techniques to human cells and embryos once validated, and (4) conducting long-term follow-up studies to monitor the health and traits of individuals born through these technologies. The text al...
3.4 parsecs

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| | crev.info

[AI summary] The article critiques the concept of natural selection and Darwinian evolution, arguing that it is a tautology and lacks a mechanistic basis for explaining the complexity of life. It discusses the concept of canalization, introduced by C.H. Waddington, and how it remains poorly understood despite decades of research. The article also highlights the limitations of systems biology in providing a comprehensive explanation for biological phenomena, suggesting that intelligent design may offer a more viable framework for understanding the complexity of life. The piece emphasizes the need for a multidisciplinary approach to studying life's mechanisms and calls for a reevaluation of current scientific paradigms.
3.4 parsecs

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| | www.greaterwrong.com

A Dr. Nigel Thomas has tried to show a logical self-contradiction in Chalmers' "Zombie World" or zombiphile argument, in a way that would convince Chalmers (given perfect rationality, of course). The argument concerns the claim that we can conceive of a near-duplicate of our world sharing all of its physical laws and containing apparent duplicates of us, who copy everything we say or do for the same physical reasons that lead us to do it, but who lack consciousness. Chalmers says this shows the logical possibility of Zombie World (though nobody believes that it actually exists.) He concludes from this that our world has a nonphysical "bridging law" saying that "systems with the same functional organization have the same sort of conscious experiences," and we...
30.3 parsecs

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