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statsandr.com | ||
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malebreastcancerblog.org
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| | | | | Disclosure: I work at the NCI, and the opinions on this blog are my own. My work at the NCI focuses on supporting people in cancer research training and is not related to clinical trials or the work on the NCI's clinical trials database. As readers of this blog know, I am not a medical... | |
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lesslikely.com
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| | | | | The Bradford Hill viewpoints are commonly used as a checklist to argue for causality when randomized trials aren't possible. However, the originator of these viewpoints never intended for them to be used this way. In this post, I examine the shortcomings of using these viewpoints as a checklist in the real world. | |
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fharrell.com
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| | | | | It is well known that the score test for comparing survival distributions between two groups without covariate adjustment, using a Cox proportional hazards (PH) model, is identical to the log-rank \chi^2 test when there are no tied failure times. Yet there persists a belief that the log-rank test is somehow completely nonparametric and does not assume PH. Log-rank and Cox approaches can only disagree if the more commonly used likelihood ratio (LR) statistic from the Cox model disagrees with the log-rank statistic (and the Cox score statistic). This article shows that in fact the log-rank and Cox LR statistics agree to a remarkable degree, and furthermore the hazard ratio arising from the log-rank test also has remarkable agreement with the Cox model counterpart. Since both methods assume PH and the log-rank test assumes within-group heterogeneity (because it doesn't allow for covariate adjustment), the Cox model actually makes fewer assumptions than log-rank. | |
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4uinews.wordpress.com
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| | | ?? ????? ???? ?? ??????? ???? ?? ???? ???? ?? ????? ?? ????? ????? ?? ????? ???? 1978 ??? ?????? ?? ?? ?? ??? ??? ????? ?????? ?? ???? ???????? ?? ?????? ???? ?? ??? ???? ?? ?????? ?? ?? ???? ??? ?? ???? ??? ?? ????? ??? ??? ?? ???????????? ?? ?? ??? ???... | ||
